Design and Optimization in Organic Synthesis PDF, ePub eBook

Design and Optimization in Organic Synthesis.pdf

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Book Summary

This is the first general textbook on experimental design and optimization in organic synthesis. The book presents a unified methodology for carrying out systematic studies when the objective is to develop efficient and optimum synthetic methods. Strategies are included both for exploring the experimental conditions and for systematic studies of entire reaction systems (substrates, reagent(s) and solvents). The methodology is based on multivariate statistical techniques. The following topics are treated in depth: classical two-level designs for screening experiments, gradient methods (steepest ascent, simplex methods) as well as response surface techniques for optimization, principal components analysis and PLS modelling. The book is intended as a hands-on text for chemists and engineers engaged in developing synthetic methods in industrial research, e.g. in fine chemicals and pharmaceuticals production, as well as for advanced undergraduate students, graduate students, and researchers in an academic environment.

File Name:Design and Optimization in Organic Synthesis
Posted By:R. Carlson
Published on 1991-11-21 by Elsevier
ISBN-10:0080868355
Status : AVAILABLE
Ratting: 4.6 of 5 | PDF File Ready to download
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